Oklahoma's seventh Governor, Henry S. Johnston, was a native to Evansville.

Edwin Denby, appointed Secretary of the Navy in 1921, was born in Evansville. He was also a notable figure in the Teapot Dome scandal.

Former MLB pitcher, Alan Benes, was born in Evansville. He played for the St. Louis Cardinals, Chicago Cubs, and Texas Rangers.

Competition swimmer and twelve-time medalist, Michael Klueh, was born in Evansville. He competed at the World Championships and the World University Games.

The 45th Governor of Indiana, Robert D. Orr, grew up in Evansville. His family has lived in the area for three generations.

Evansville native, Suzanne Crouch, is the 52nd and current Lieutenant Governor of Indiana. She graduated from Mater Dei High School.

Mary Fendrich Hulman nació en Evansville y era hija del presidente de Fendrich Cigar Company, John H. Fendrich. Se casó con Tony Hulman, quien compró el Indianapolis Motor Speedway después de la Segunda Guerra Mundial.

Sallie Wyatt Stewart creció en Evansville y sirvió a una maestra local antes de convertirse en presidenta de la Federación de Mujeres de Color de Indiana. Finalmente fue elegida presidenta de la Asociación Nacional de Mujeres de Color hasta 1933.

Albion Fellows Bacon was an American social reformer and writer known for her work to improve the lives of Indiana's youth.

Don Mattingly, former MLB player for the NY Yankees and current manager of the Miami Marlins, was born and raised in Evansville. He attended Reitz Memorial High School and also played American Legion baseball for Funkhouser Post #8. Mattingly was drafted in the 19th round of the 1979 MLB draft.