Born in Evansville, Elbert Frank Cox was a mathematician and the first African American to receive a Ph.D. in Mathematics.

The Southern Indiana Career & Technical Center was named on the top 5 career and technical schools in the nation.

En 2019, Signature School fue clasificada como el no. 1 escuela secundaria más desafiante en el país por el escritor de educación Jay Mathews.

En 2019, Signature School fue clasificada como el no. 10 mejores escuelas secundarias públicas por U.S.World News & Report.

The University of Evansville has been designated as a Changemaker Campus by Ashoka U for its role as a leader in social innovation and changemaking in higher education.

A team of students and professors at USI, alongside NASA, sent the UNITE CubeSat into space in late 2018. It measures plasma properties in the lower ionosphere.

Henry Babcock Veatch, born in Evansville in 1911, was a respected American philosopher and college professor

Margaret K. Butler contributed to the development of early computers. She was the first female fellow at the American Nuclear Society and director of the National Energy Software Center.

Birthplace of Paul Musgrave, an assistant professor at UMass Amherst and an expert in foreign policy and foreign affairs.

John Duncan Wiley is a faculty member and the former 28th chancellor of the University of Wisconsin–Madison. He was born here in 1942.